Cleft pathways

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Cleft Lip and Cleft Palate

Cleft lip (cheiloschisis) and cleft palate (palatoschisis) can occur individual or together. Individuals with CLP may experience problems with feeding, speaking, hearing and social integration that can be corrected to varying degrees by surgery, dental treatment, speech therapy and psychological intervention. In India over 35,000 babies per year are affected. This review signifies the etiologic...

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Unilateral cleft hand with cleft foot.

Congenital anomalies of the hand form an important class of congenital malformations. They have a huge functional importance because of the part played by the hand in the daily activities of a person. The deformities also have significant cosmetic significance and may also be associated with other anomalies. Amongst the congenital anomalies, central deficiency or cleft hand is relatively rare. ...

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Cleft Palate

An infant born with a cleft palate inherits many handicaps. Unable to develop intraoral negative pressure, he cannot suckle and hence cannot feed in a normal fashion. Furthermore, on swallowing, he expels his feedings through the nose. The open cleft, because of failure to warm and moisten the inspired air, produces a continuing sore throat. The middle ears become secondarily involved with sero...

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Converse : Chapter 47 Secondary Deformities of Cleft Lip , Cleft Lip and Nose , and Cleft Palate

The diversity of secondary deformities following repair of the cleft lip and nose is striking. The deformities reflect the wide variety of surgical techniques used to repair the cleft lip and the cleft lip nose. Secondary deformities of the repaired cleft lip and nose result from several distinct but related components: congenitally abnormal tissues; surgically modified tissues; the innate tend...

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FOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate.

Nonsyndromic orofacial clefts are a common complex birth defect caused by genetic and environmental factors and/or their interactions. A previous genome-wide linkage scan discovered a novel locus for cleft lip with or without cleft palate (CL/P) at 9q22-q33. To identify the etiologic gene, we undertook an iterative and complementary fine mapping strategy using family-based CL/P samples from Col...

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ژورنال

عنوان ژورنال: British Dental Journal

سال: 2011

ISSN: 0007-0610,1476-5373

DOI: 10.1038/sj.bdj.2011.392